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Tamoxifen

Synonyms

SourcesNames Used
GDSC1000, GRAYTamoxifen
CTRPv2tamoxifen
PharmacoGx Tamoxifen

External IDs

DatabaseIdentifier
Smiles: [H+].[H+].[H+].CCC(=C(C1=CC=CC=C1)C2=CC=C(C=C2)OCCN(C)C)C3=CC=CC=C3.C(C(=O)[O-])C(CC(=O)[O-])(C(=O)[O-])O
Inchikey: FQZYTYWMLGAPFJ-OQKDUQJOSA-N
Pubchem: 25010734

Annotated Targets

EBP, ESR1, ESR2, GPER1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PRKCI, PRKCQ, PRKCZ

Cell lines tested with Tamoxifen

1279 cell lines have been tested with this compound, using data from 3 dataset(s).
MDA-MB-361 breast GDSC1000, GRAY, CTRPv27
HCC1954 breast GDSC1000, GRAY, CTRPv27
HCC1419 breast GDSC1000, GRAY, CTRPv27
HCC2185 breast GRAY6
MDA-MB-468 breast GDSC1000, GRAY, CTRPv26
HCC1395 breast GDSC1000, GRAY, CTRPv26
HCC202 breast GDSC1000, GRAY, CTRPv26
HCC1569 breast GDSC1000, GRAY, CTRPv26
MDA-MB-231 breast GDSC1000, GRAY, CTRPv26
Hs-578-T breast GDSC1000, GRAY5
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Top molecular features associated with response to Tamoxifen


Feature TypeStandardized
Nominal ANOVA
mRNA TG CTRPv2 AAC 0.21 6e-09
mRNA TPO CTRPv2 AAC 0.21 2e-08
mRNA SST CTRPv2 AAC 0.2 4e-08
mRNA CDC20B GDSC1000 AAC 0.18 6e-08
mRNA GPR83 GDSC1000 AAC 0.18 1e-07
mRNA ADAMTS10 CTRPv2 AAC 0.19 1e-06
mRNA DIO1 CTRPv2 AAC 0.18 2e-06
mRNA RDH10 CTRPv2 AAC 0.18 2e-06
mRNA SYNPO CTRPv2 AAC 0.19 7e-06
mRNA ATOH1 GDSC1000 AAC 0.15 8e-06
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