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TAK-715

Synonyms

SourcesNames Used
GDSC1000TAK-715
PharmacoGx TAK-715

External IDs

DatabaseIdentifier
Smiles: CCc1nc(c(s1)-c1ccnc(NC(=O)c2ccccc2)c1)-c1cccc(C)c1
Pubchem: 9952773

Annotated Targets

MAPK14

Cell lines tested with TAK-715

984 cell lines have been tested with this compound, using data from 1 dataset(s).
NCI-H2009 lung GDSC10001
MOLP-8 haematopoietic and lymphoid tissue GDSC10001
GR-ST haematopoietic and lymphoid tissue GDSC10001
OVCAR-3 ovary GDSC10001
CAL-12T lung GDSC10001
MDA-MB-415 breast GDSC10001
SK-LU-1 lung GDSC10001
LP-1 haematopoietic and lymphoid tissue GDSC10001
BICR 22 upper aerodigestive tract GDSC10001
EKVX lung GDSC10001
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Top molecular features associated with response to TAK-715


Feature TypeStandardized
Nominal ANOVA
mRNA CD247 GDSC1000 AAC 0.25 2e-13
mRNA CD3G GDSC1000 AAC 0.23 3e-12
mRNA CCR8 GDSC1000 AAC 0.21 4e-11
mRNA GIMAP6 GDSC1000 AAC 0.22 1e-10
mRNA CD3E GDSC1000 AAC 0.21 3e-10
mRNA CD1A GDSC1000 AAC 0.2 4e-10
mRNA ITK GDSC1000 AAC 0.22 5e-10
mRNA CD2 GDSC1000 AAC 0.2 1e-09
mRNA RPS4Y2 GDSC1000 AAC 0.19 1e-09
mRNA TRAT1 GDSC1000 AAC 0.19 3e-09
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