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TAE684

Synonyms

SourcesNames Used
CCLE, GDSC1000TAE684
CTRPv2NVP-TAE684
PharmacoGx TAE684

External IDs

DatabaseIdentifier
Smiles: CC(C)S(=O)(=O)C1=CC=CC=C1NC2=NC(=NC=C2Cl)NC3=C(C=C(C=C3)N4CCC(CC4)N5CCN(CC5)C)OC
Inchikey: QQWUGDVOUVUTOY-UHFFFAOYSA-N
Pubchem: 16038120

Cell lines tested with TAE684

1126 cell lines have been tested with this compound, using data from 3 dataset(s).
P3HR-1 haematopoietic and lymphoid tissue CCLE, GDSC1000, CTRPv24
NCI-H1869 lung CCLE, GDSC1000, CTRPv24
NCI-H1299 lung CCLE, GDSC1000, CTRPv24
LOXIMVI haematopoietic and lymphoid tissue CCLE, GDSC1000, CTRPv24
A549 lung CCLE, CTRPv24
UACC-257 haematopoietic and lymphoid tissue CCLE, GDSC1000, CTRPv23
U-87-MG central nervous system CCLE, GDSC1000, CTRPv23
Toledo haematopoietic and lymphoid tissue CCLE, GDSC1000, CTRPv23
TE-9 oesophagus CCLE, GDSC1000, CTRPv23
TE-5 oesophagus CCLE, GDSC1000, CTRPv23
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Top molecular features associated with response to TAE684


Feature TypeStandardized
Nominal ANOVA
mRNA ALK GDSC1000 AAC 0.5 4e-24
mRNA TMEM260 CTRPv2 AAC 0.3 9e-20
mRNA IL2RA CTRPv2 AAC 0.3 2e-19
mRNA GAS1 CTRPv2 AAC 0.29 7e-18
mRNA IL26 GDSC1000 AAC 0.41 2e-17
mRNA WNT8B CTRPv2 AAC 0.29 2e-17
mRNA SERPINA1 GDSC1000 AAC 0.42 3e-17
mRNA GZMB GDSC1000 AAC 0.4 2e-16
mRNA TMPRSS11D GDSC1000 AAC 0.4 2e-16
mRNA ZBTB46 GDSC1000 AAC 0.4 4e-16
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