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tacrolimus

Synonyms

SourcesNames Used
CTRPv2tacrolimus
PharmacoGx tacrolimus

External IDs

DatabaseIdentifier
Smiles: CC1CC(C2C(CC(C(O2)(C(=O)C(=O)N3CCCCC3C(=O)OC(C(C(CC(=O)C(C=C(C1)C)CC=C)O)C)C(=CC4CCC(C(C4)OC)O)C)O)C)OC)OC
Inchikey: QJJXYPPXXYFBGM-LFZNUXCKSA-N
Pubchem: 445643

Annotated Targets

FKBP1A, PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2

Cell lines tested with tacrolimus

798 cell lines have been tested with this compound, using data from 1 dataset(s).
A549 lung CTRPv23
DU-145 prostate CTRPv22
AsPC-1 pancreas CTRPv22
NCI-H1869 lung CTRPv22
CCF-STTG1 central nervous system CTRPv22
OAW-28 ovary CTRPv22
HeLa cervix CTRPv22
LOXIMVI haematopoietic and lymphoid tissue CTRPv22
NCI-H520 lung CTRPv22
MKN74 stomach CTRPv22
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Top molecular features associated with response to tacrolimus


Feature TypeStandardized
Nominal ANOVA
mRNA PAN3 CTRPv2 AAC 0.32 1e-20
mRNA ARPP21 CTRPv2 AAC 0.28 1e-15
mRNA ESRRG CTRPv2 AAC 0.27 2e-14
mRNA DGAT2L6 CTRPv2 AAC 0.26 6e-14
mRNA ERMN CTRPv2 AAC 0.28 2e-13
mRNA ZCCHC7 CTRPv2 AAC 0.27 2e-13
mRNA TAPT1 CTRPv2 AAC 0.27 4e-13
mRNA FLT3 CTRPv2 AAC 0.24 1e-12
mRNA CSNK1G2 CTRPv2 AAC 0.26 3e-12
mRNA CPNE9 CTRPv2 AAC 0.23 2e-11
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