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tacedinaline

Synonyms

SourcesNames Used
CTRPv2tacedinaline
PharmacoGx tacedinaline

External IDs

DatabaseIdentifier
Smiles: CC(=O)Nc1ccc(cc1)C(=O)Nc2ccccc2N
Pubchem: 2746

Annotated Targets

HDAC1, HDAC2, HDAC3, HDAC6, HDAC8

Cell lines tested with tacedinaline

607 cell lines have been tested with this compound, using data from 1 dataset(s).
DU-145 prostate CTRPv22
NCI-H1869 lung CTRPv22
CCF-STTG1 central nervous system CTRPv22
OAW-28 ovary CTRPv22
HeLa cervix CTRPv22
LOXIMVI haematopoietic and lymphoid tissue CTRPv22
A549 lung CTRPv22
NCI-H520 lung CTRPv22
MKN74 stomach CTRPv22
IGROV-1 ovary CTRPv22
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Top molecular features associated with response to tacedinaline


Feature TypeStandardized
Nominal ANOVA
mRNA MBTD1 CTRPv2 AAC 0.28 1e-10
mRNA OTC CTRPv2 AAC 0.23 9e-10
mRNA OR1Q1 CTRPv2 AAC 0.22 1e-09
mRNA PCK1 CTRPv2 AAC 0.23 1e-09
mRNA MLXIPL CTRPv2 AAC 0.24 2e-09
mRNA TPO CTRPv2 AAC 0.21 4e-09
mRNA FBRSL1 CTRPv2 AAC 0.23 7e-09
mRNA TIA1 CTRPv2 AAC 0.22 2e-08
mRNA SST CTRPv2 AAC 0.2 2e-08
mRNA TG CTRPv2 AAC 0.2 2e-08
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