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SNX-2112

Synonyms

SourcesNames Used
GDSC1000, CTRPv2SNX-2112
PharmacoGx SNX-2112

External IDs

DatabaseIdentifier
Smiles: CC1(CC2=C(C(=O)C1)C(=NN2C3=CC(=C(C=C3)C(=O)N)NC4CCC(CC4)O)C(F)(F)F)C
Inchikey: ZFVRYNYOPQZKDG-UHFFFAOYSA-N
Pubchem: 24772860

Annotated Targets

HSP90AA1, HSP90B1

Cell lines tested with SNX-2112

1288 cell lines have been tested with this compound, using data from 2 dataset(s).
A549 lung CTRPv23
OAW-28 ovary GDSC1000, CTRPv23
NCI-H1299 lung GDSC1000, CTRPv23
CAL-51 breast GDSC1000, CTRPv23
NCI-H1869 lung GDSC1000, CTRPv23
LOXIMVI haematopoietic and lymphoid tissue GDSC1000, CTRPv23
NCI-H460 lung GDSC1000, CTRPv23
P3HR-1 haematopoietic and lymphoid tissue GDSC1000, CTRPv23
CCF-STTG1 central nervous system GDSC1000, CTRPv23
AsPC-1 pancreas GDSC1000, CTRPv23
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Top molecular features associated with response to SNX-2112


Feature TypeStandardized
Nominal ANOVA
mRNA NCKAP1L GDSC1000 AAC 0.34 6e-12
mRNA CCAR1 GDSC1000 AAC 0.21 2e-10
mRNA SLC35F5 GDSC1000 AAC -0.21 2e-10
mRNA BUB3 GDSC1000 AAC 0.2 3e-10
mRNA KHDRBS1 GDSC1000 AAC 0.2 9e-10
mRNA CTSA GDSC1000 AAC -0.21 9e-10
mRNA SRSF11 GDSC1000 AAC 0.19 1e-09
mRNA BTAF1 GDSC1000 AAC 0.19 1e-09
mRNA PNISR GDSC1000 AAC 0.19 1e-09
mRNA HNRNPDL GDSC1000 AAC 0.2 1e-09
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