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SKI-II

Synonyms

SourcesNames Used
CTRPv2SKI-II
PharmacoGx SKI-II

External IDs

DatabaseIdentifier
Smiles: C1=CC(=CC=C1C2=CSC(=N2)NC3=CC=C(C=C3)O)Cl
Inchikey: ZFGXZJKLOFCECI-UHFFFAOYSA-N
Pubchem: 753704

Annotated Targets

SPHK1

Cell lines tested with SKI-II

805 cell lines have been tested with this compound, using data from 1 dataset(s).
A549 lung CTRPv23
DU-145 prostate CTRPv22
AsPC-1 pancreas CTRPv22
NCI-H1869 lung CTRPv22
CCF-STTG1 central nervous system CTRPv22
OAW-28 ovary CTRPv22
HeLa cervix CTRPv22
LOXIMVI haematopoietic and lymphoid tissue CTRPv22
NCI-H520 lung CTRPv22
MKN74 stomach CTRPv22
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Top molecular features associated with response to SKI-II


Feature TypeStandardized
Nominal ANOVA
mRNA FAM117B CTRPv2 AAC 0.28 4e-13
mRNA LIG4 CTRPv2 AAC 0.24 2e-10
mRNA CBX2 CTRPv2 AAC 0.26 5e-10
mRNA ZNF107 CTRPv2 AAC 0.24 2e-09
mRNA E2F2 CTRPv2 AAC 0.25 3e-09
mRNA ANKRD17 CTRPv2 AAC 0.22 4e-09
mRNA SOX4 CTRPv2 AAC 0.21 4e-09
mRNA TIA1 CTRPv2 AAC 0.22 5e-09
mRNA N4BP2 CTRPv2 AAC 0.23 5e-09
mRNA CTCF CTRPv2 AAC 0.24 1e-08
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