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sitagliptin

Synonyms

SourcesNames Used
CTRPv2sitagliptin
PharmacoGx sitagliptin

External IDs

DatabaseIdentifier
Smiles: N[C@@H](CC(=O)N1CCn2c(nnc2C1)C(F)(F)F)Cc3cc(F)c(F)cc3F
Pubchem: 4369359

Annotated Targets

DPP4

Cell lines tested with sitagliptin

212 cell lines have been tested with this compound, using data from 1 dataset(s).
NCI-H1299 lung CTRPv22
SUIT-2 pancreas CTRPv22
YD-38 upper aerodigestive tract CTRPv21
YD-15 salivary gland CTRPv21
YD-10B upper aerodigestive tract CTRPv21
TE-9 oesophagus CTRPv21
TE-10 oesophagus CTRPv21
SNU-899 upper aerodigestive tract CTRPv21
SNU-668 stomach CTRPv21
SNU-5 stomach CTRPv21
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Top molecular features associated with response to sitagliptin


Feature TypeStandardized
Nominal ANOVA
mRNA PGAP3 CTRPv2 AAC 0.38 1e-08
mRNA PRSS58 CTRPv2 AAC 0.38 2e-08
mRNA GRB7 CTRPv2 AAC 0.38 2e-08
mRNA STARD3 CTRPv2 AAC 0.37 3e-08
mRNA NAALADL2 CTRPv2 AAC 0.4 3e-08
mRNA FABP2 CTRPv2 AAC 0.4 4e-08
mRNA REG1B CTRPv2 AAC 0.37 1e-07
mRNA MIEN1 CTRPv2 AAC 0.35 2e-07
mRNA KLRG2 CTRPv2 AAC 0.38 2e-07
mRNA NXPE4 CTRPv2 AAC 0.37 2e-07
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