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simvastatin

Synonyms

SourcesNames Used
CTRPv2simvastatin
PharmacoGx simvastatin

External IDs

DatabaseIdentifier
Smiles: CCC(C)(C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)[C@@H]12
Inchikey: RYMZZMVNJRMUDD-HGQWONQESA-N
Pubchem: 54454

Annotated Targets

HMGCR, ITGB2

Cell lines tested with simvastatin

759 cell lines have been tested with this compound, using data from 1 dataset(s).
A549 lung CTRPv23
DU-145 prostate CTRPv22
NCI-H1869 lung CTRPv22
CCF-STTG1 central nervous system CTRPv22
OAW-28 ovary CTRPv22
LOXIMVI haematopoietic and lymphoid tissue CTRPv22
MKN74 stomach CTRPv22
IGROV-1 ovary CTRPv22
P3HR-1 haematopoietic and lymphoid tissue CTRPv22
CAL-51 breast CTRPv22
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Top molecular features associated with response to simvastatin


Feature TypeStandardized
Nominal ANOVA
mRNA ADAMTS6 CTRPv2 AAC 0.29 8e-14
mRNA TEX13B CTRPv2 AAC 0.26 9e-12
mRNA FAM9A CTRPv2 AAC 0.25 4e-11
mRNA CCDC172 CTRPv2 AAC 0.22 8e-09
mRNA RP13-347D8.7 CTRPv2 AAC 0.2 1e-07
mRNA AC006386.1 CTRPv2 AAC 0.19 7e-07
mRNA KRTAP2-3 CTRPv2 AAC 0.18 1e-06
mRNA COL13A1 CTRPv2 AAC 0.19 2e-06
mRNA NMT2 CTRPv2 AAC 0.19 4e-06
mRNA MAP7D1 CTRPv2 AAC 0.2 4e-06
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