1. Home/
  2. Compounds/
  3. Sildenafil

Sildenafil

Synonyms

SourcesNames Used
CTRPv2sildenafil
PharmacoGx Sildenafil

External IDs

DatabaseIdentifier
Smiles: CCCC1=NN(C2=C1NC(=NC2=O)C3=C(C=CC(=C3)S(=O)(=O)N4CCN(CC4)C)OCC)C
Inchikey: BNRNXUUZRGQAQC-UHFFFAOYSA-N
Pubchem: 5212

Annotated Targets

PDE5A, PDE6G, PDE6H, SLCO1B1, SLCO1B3

Cell lines tested with Sildenafil

813 cell lines have been tested with this compound, using data from 1 dataset(s).
A549 lung CTRPv23
DU-145 prostate CTRPv22
AsPC-1 pancreas CTRPv22
NCI-H1869 lung CTRPv22
CCF-STTG1 central nervous system CTRPv22
OAW-28 ovary CTRPv22
HeLa cervix CTRPv22
LOXIMVI haematopoietic and lymphoid tissue CTRPv22
NCI-H520 lung CTRPv22
MKN74 stomach CTRPv22
Download CSV
Download Data as CSV

Top molecular features associated with response to Sildenafil


Feature TypeStandardized
Nominal ANOVA
mRNA HIGD1C CTRPv2 AAC 0.25 3e-10
mRNA C11orf96 CTRPv2 AAC 0.23 6e-08
mRNA MYH1 CTRPv2 AAC 0.2 6e-08
mRNA GALNT9 CTRPv2 AAC 0.21 8e-08
mRNA C14orf177 CTRPv2 AAC 0.19 1e-07
mRNA GGT5 CTRPv2 AAC 0.19 2e-07
mRNA LLNLF-187D8.1 CTRPv2 AAC 0.21 3e-07
mRNA CRABP1 CTRPv2 AAC 0.2 7e-07
mRNA POLE4 CTRPv2 AAC -0.19 9e-07
mRNA MYH2 CTRPv2 AAC 0.18 1e-06
Download CSV