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SGX-523

Synonyms

SourcesNames Used
CTRPv2SGX-523
PharmacoGx SGX-523

External IDs

DatabaseIdentifier
Smiles: Cn1cc(cn1)-c1ccc2nnc(Sc3ccc4ncccc4c3)n2n1
Pubchem: 24779724

Annotated Targets

MET

Cell lines tested with SGX-523

839 cell lines have been tested with this compound, using data from 1 dataset(s).
A549 lung CTRPv23
DU-145 prostate CTRPv22
AsPC-1 pancreas CTRPv22
NCI-H1869 lung CTRPv22
CCF-STTG1 central nervous system CTRPv22
OAW-28 ovary CTRPv22
HeLa cervix CTRPv22
LOXIMVI haematopoietic and lymphoid tissue CTRPv22
NCI-H520 lung CTRPv22
MKN74 stomach CTRPv22
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Top molecular features associated with response to SGX-523


Feature TypeStandardized
Nominal ANOVA
mRNA MET CTRPv2 AAC 0.61 2e-62
mRNA CAPZA2 CTRPv2 AAC 0.56 7e-58
mRNA PGC CTRPv2 AAC 0.39 8e-29
mRNA CAV2 CTRPv2 AAC 0.41 5e-27
mRNA FRS3 CTRPv2 AAC 0.35 2e-22
mRNA KRTAP21-3 CTRPv2 AAC 0.34 4e-22
mRNA ST7 CTRPv2 AAC 0.34 4e-21
mRNA C6orf132 CTRPv2 AAC 0.34 1e-19
mRNA PRICKLE4 CTRPv2 AAC 0.32 2e-19
mRNA TRERF1 CTRPv2 AAC 0.32 3e-19
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