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serdemetan

Synonyms

SourcesNames Used
FIMMSerdemetan
PharmacoGx serdemetan

External IDs

DatabaseIdentifier
Smiles: C(Cc1c[nH]c2ccccc12)Nc1cccc(Nc2ccncc2)c1
Pubchem: 11609586

Annotated Targets

MDM2

Cell lines tested with serdemetan

50 cell lines have been tested with this compound, using data from 1 dataset(s).
SR haematopoietic and lymphoid tissue FIMM1
SIG-M5 haematopoietic and lymphoid tissue FIMM1
RPMI-8226 haematopoietic and lymphoid tissue FIMM1
THP-1 haematopoietic and lymphoid tissue FIMM1
SKM-1 haematopoietic and lymphoid tissue FIMM1
PC-3 prostate FIMM1
OVCAR-8 ovary FIMM1
OVCAR-5 ovary FIMM1
OVCAR-4 ovary FIMM1
OVCAR-3 ovary FIMM1
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Tissues tested with serdemetan

4 tissues have been tested with this compound, using data from 1 dataset(s).
breastFIMM21
haematopoietic and lymphoid tissueFIMM17
ovaryFIMM11
prostateFIMM1
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Download Data as CSV

Top molecular features associated with response to serdemetan


Feature TypeStandardized
Nominal ANOVA
mRNA VASH1 FIMM AAC 0.76 4e-05
mRNA ACP1 FIMM AAC -0.56 5e-05
mRNA CCL2 FIMM AAC 0.53 0.0001
mRNA ZBTB7A FIMM AAC 0.59 0.0001
mRNA MSH2 FIMM AAC -0.52 0.0002
mRNA ANKRD46 FIMM AAC -0.55 0.0002
mRNA AMD1 FIMM AAC -0.55 0.0002
mRNA ACP6 FIMM AAC -0.63 0.0002
mRNA PEX13 FIMM AAC -0.57 0.0003
mRNA VENTX FIMM AAC 0.56 0.0003
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