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semagacestat

Synonyms

SourcesNames Used
CTRPv2semagacestat
PharmacoGx semagacestat

External IDs

DatabaseIdentifier
Pubchem: 9843750

Annotated Targets

PSEN1, APH1A, NCSTN, PSENEN

Cell lines tested with semagacestat

848 cell lines have been tested with this compound, using data from 1 dataset(s).
A549 lung CTRPv23
DU-145 prostate CTRPv22
AsPC-1 pancreas CTRPv22
NCI-H1869 lung CTRPv22
CCF-STTG1 central nervous system CTRPv22
OAW-28 ovary CTRPv22
HeLa cervix CTRPv22
LOXIMVI haematopoietic and lymphoid tissue CTRPv22
NCI-H520 lung CTRPv22
MKN74 stomach CTRPv22
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Top molecular features associated with response to semagacestat


Feature TypeStandardized
Nominal ANOVA
mRNA TEX33 CTRPv2 AAC 0.23 8e-11
mRNA ARHGDIG CTRPv2 AAC 0.21 2e-08
mRNA SERPINB5 CTRPv2 AAC 0.21 2e-06
mRNA DISP2 CTRPv2 AAC 0.18 2e-06
mRNA MALRD1 CTRPv2 AAC 0.17 3e-06
mRNA AC100821.1 CTRPv2 AAC 0.17 5e-06
mRNA BTNL8 CTRPv2 AAC 0.16 9e-06
mRNA SPRR2F CTRPv2 AAC 0.16 1e-05
mRNA TNFRSF21 CTRPv2 AAC 0.18 1e-05
mRNA REG4 CTRPv2 AAC 0.16 1e-05
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