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selumetinib:vorinostat (8:1 mol/mol)

Synonyms

SourcesNames Used
CTRPv2selumetinib:vorinostat (8:1 mol/mol)
PharmacoGx selumetinib:vorinostat (8:1 mol/mol)

Cell lines tested with selumetinib:vorinostat (8:1 mol/mol)

757 cell lines have been tested with this compound, using data from 1 dataset(s).
A549 lung CTRPv23
DU-145 prostate CTRPv22
AsPC-1 pancreas CTRPv22
NCI-H1869 lung CTRPv22
CCF-STTG1 central nervous system CTRPv22
OAW-28 ovary CTRPv22
HeLa cervix CTRPv22
MKN74 stomach CTRPv22
IGROV-1 ovary CTRPv22
P3HR-1 haematopoietic and lymphoid tissue CTRPv22
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Tissues tested with selumetinib:vorinostat (8:1 mol/mol)

25 tissues have been tested with this compound, using data from 1 dataset(s).
haematopoietic and lymphoid tissueCTRPv2131
lungCTRPv2130
large intestineCTRPv247
N/ACTRPv242
skinCTRPv242
ovaryCTRPv240
pancreasCTRPv239
breastCTRPv237
central nervous systemCTRPv237
stomachCTRPv232
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Top molecular features associated with response to selumetinib:vorinostat (8:1 mol/mol)


Feature TypeStandardized
Nominal ANOVA
mRNA RP11-307N16.6 CTRPv2 AAC 0.27 4e-11
mRNA ZFP36L2 CTRPv2 AAC 0.25 2e-10
mRNA SPATA13 CTRPv2 AAC 0.25 5e-10
mRNA IRF2BP2 CTRPv2 AAC 0.23 1e-09
mRNA GRAMD4 CTRPv2 AAC 0.23 4e-09
mRNA RPP25 CTRPv2 AAC 0.22 5e-09
mRNA ATP1A1 CTRPv2 AAC 0.23 6e-09
mRNA MGST2 CTRPv2 AAC 0.21 7e-09
mRNA GPR35 CTRPv2 AAC 0.23 1e-08
mRNA FGF2 CTRPv2 AAC -0.22 1e-08
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