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selumetinib:PLX-4032 (8:1 mol/mol)

Synonyms

SourcesNames Used
CTRPv2selumetinib:PLX-4032 (8:1 mol/mol)
PharmacoGx selumetinib:PLX-4032 (8:1 mol/mol)

Cell lines tested with selumetinib:PLX-4032 (8:1 mol/mol)

835 cell lines have been tested with this compound, using data from 1 dataset(s).
A549 lung CTRPv23
DU-145 prostate CTRPv22
NCI-H1869 lung CTRPv22
CCF-STTG1 central nervous system CTRPv22
OAW-28 ovary CTRPv22
HeLa cervix CTRPv22
LOXIMVI haematopoietic and lymphoid tissue CTRPv22
NCI-H520 lung CTRPv22
MKN74 stomach CTRPv22
IGROV-1 ovary CTRPv22
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Tissues tested with selumetinib:PLX-4032 (8:1 mol/mol)

25 tissues have been tested with this compound, using data from 1 dataset(s).
haematopoietic and lymphoid tissueCTRPv2151
lungCTRPv2141
N/ACTRPv248
central nervous systemCTRPv247
large intestineCTRPv245
skinCTRPv243
ovaryCTRPv241
pancreasCTRPv240
breastCTRPv239
stomachCTRPv234
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Top molecular features associated with response to selumetinib:PLX-4032 (8:1 mol/mol)


Feature TypeStandardized
Nominal ANOVA
mRNA SPRY2 CTRPv2 AAC 0.32 2e-17
mRNA SH3TC2 CTRPv2 AAC 0.32 8e-15
mRNA GKAP1 CTRPv2 AAC -0.28 1e-14
mRNA SPECC1L-ADORA2A CTRPv2 AAC -0.26 1e-12
mRNA LYST CTRPv2 AAC 0.26 3e-12
mRNA ZFP36L2 CTRPv2 AAC 0.26 5e-12
mRNA SLC35D2 CTRPv2 AAC 0.3 5e-12
mRNA ACY1 CTRPv2 AAC 0.26 7e-12
mRNA SPRY4 CTRPv2 AAC 0.26 1e-11
mRNA WDR76 CTRPv2 AAC -0.26 1e-11
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