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selumetinib:piperlongumine (8:1 mol/mol)

Synonyms

SourcesNames Used
CTRPv2selumetinib:piperlongumine (8:1 mol/mol)
PharmacoGx selumetinib:piperlongumine (8:1 mol/mol)

Cell lines tested with selumetinib:piperlongumine (8:1 mol/mol)

805 cell lines have been tested with this compound, using data from 1 dataset(s).
A549 lung CTRPv23
DU-145 prostate CTRPv22
AsPC-1 pancreas CTRPv22
NCI-H1869 lung CTRPv22
CCF-STTG1 central nervous system CTRPv22
OAW-28 ovary CTRPv22
HeLa cervix CTRPv22
LOXIMVI haematopoietic and lymphoid tissue CTRPv22
NCI-H520 lung CTRPv22
MKN74 stomach CTRPv22
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Tissues tested with selumetinib:piperlongumine (8:1 mol/mol)

25 tissues have been tested with this compound, using data from 1 dataset(s).
lungCTRPv2140
haematopoietic and lymphoid tissueCTRPv2135
N/ACTRPv247
large intestineCTRPv246
skinCTRPv243
central nervous systemCTRPv243
pancreasCTRPv240
ovaryCTRPv240
breastCTRPv240
upper aerodigestive tractCTRPv232
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Top molecular features associated with response to selumetinib:piperlongumine (8:1 mol/mol)


Feature TypeStandardized
Nominal ANOVA
mRNA ZFP36L2 CTRPv2 AAC 0.28 3e-14
mRNA IRF2BP2 CTRPv2 AAC 0.25 7e-12
mRNA LYST CTRPv2 AAC 0.24 1e-10
mRNA SH3TC2 CTRPv2 AAC 0.25 5e-10
mRNA SPRY2 CTRPv2 AAC 0.23 5e-10
mRNA SPRY4 CTRPv2 AAC 0.23 1e-09
mRNA TNFRSF1B CTRPv2 AAC 0.21 6e-09
mRNA ACY1 CTRPv2 AAC 0.22 8e-09
mRNA CEBPA CTRPv2 AAC 0.2 9e-09
mRNA GPR35 CTRPv2 AAC 0.22 1e-08
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