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selumetinib:MK-2206 (8:1 mol/mol)

Synonyms

SourcesNames Used
CTRPv2selumetinib:MK-2206 (8:1 mol/mol)
PharmacoGx selumetinib:MK-2206 (8:1 mol/mol)

Cell lines tested with selumetinib:MK-2206 (8:1 mol/mol)

832 cell lines have been tested with this compound, using data from 1 dataset(s).
A549 lung CTRPv23
DU-145 prostate CTRPv22
NCI-H1869 lung CTRPv22
CCF-STTG1 central nervous system CTRPv22
OAW-28 ovary CTRPv22
HeLa cervix CTRPv22
LOXIMVI haematopoietic and lymphoid tissue CTRPv22
NCI-H520 lung CTRPv22
MKN74 stomach CTRPv22
IGROV-1 ovary CTRPv22
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Tissues tested with selumetinib:MK-2206 (8:1 mol/mol)

25 tissues have been tested with this compound, using data from 1 dataset(s).
haematopoietic and lymphoid tissueCTRPv2149
lungCTRPv2140
N/ACTRPv247
central nervous systemCTRPv247
large intestineCTRPv245
skinCTRPv244
pancreasCTRPv240
ovaryCTRPv240
breastCTRPv240
stomachCTRPv234
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Top molecular features associated with response to selumetinib:MK-2206 (8:1 mol/mol)


Feature TypeStandardized
Nominal ANOVA
mRNA ZFP36L2 CTRPv2 AAC 0.25 1e-11
mRNA PRPS1 CTRPv2 AAC -0.24 3e-11
mRNA GPR35 CTRPv2 AAC 0.24 9e-10
mRNA SCN8A CTRPv2 AAC -0.23 1e-09
mRNA KRBOX4 CTRPv2 AAC -0.22 1e-09
mRNA GKAP1 CTRPv2 AAC -0.22 2e-09
mRNA SENP1 CTRPv2 AAC -0.22 3e-09
mRNA SPRY2 CTRPv2 AAC 0.23 3e-09
mRNA SGTB CTRPv2 AAC -0.22 6e-09
mRNA SH3TC2 CTRPv2 AAC 0.24 6e-09
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