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selumetinib:GDC-0941 (4:1 mol/mol)

Synonyms

SourcesNames Used
CTRPv2selumetinib:GDC-0941 (4:1 mol/mol)
PharmacoGx selumetinib:GDC-0941 (4:1 mol/mol)

Cell lines tested with selumetinib:GDC-0941 (4:1 mol/mol)

833 cell lines have been tested with this compound, using data from 1 dataset(s).
A549 lung CTRPv23
DU-145 prostate CTRPv22
AsPC-1 pancreas CTRPv22
NCI-H1869 lung CTRPv22
CCF-STTG1 central nervous system CTRPv22
OAW-28 ovary CTRPv22
HeLa cervix CTRPv22
LOXIMVI haematopoietic and lymphoid tissue CTRPv22
MKN74 stomach CTRPv22
IGROV-1 ovary CTRPv22
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Tissues tested with selumetinib:GDC-0941 (4:1 mol/mol)

25 tissues have been tested with this compound, using data from 1 dataset(s).
haematopoietic and lymphoid tissueCTRPv2150
lungCTRPv2143
N/ACTRPv248
large intestineCTRPv247
central nervous systemCTRPv246
skinCTRPv245
pancreasCTRPv240
ovaryCTRPv240
breastCTRPv238
upper aerodigestive tractCTRPv232
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Top molecular features associated with response to selumetinib:GDC-0941 (4:1 mol/mol)


Feature TypeStandardized
Nominal ANOVA
mRNA IRF2BP2 CTRPv2 AAC 0.22 2e-09
mRNA SGTB CTRPv2 AAC -0.22 5e-09
mRNA ZFP36L2 CTRPv2 AAC 0.22 5e-09
mRNA GKAP1 CTRPv2 AAC -0.21 2e-08
mRNA ACY1 CTRPv2 AAC 0.21 2e-08
mRNA SPI1 CTRPv2 AAC 0.23 4e-08
mRNA LYST CTRPv2 AAC 0.21 5e-08
mRNA CEBPA CTRPv2 AAC 0.2 5e-08
mRNA PIWIL4 CTRPv2 AAC 0.2 7e-08
mRNA KIAA0930 CTRPv2 AAC 0.2 8e-08
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