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SB590885

Synonyms

SourcesNames Used
GDSC1000SB590885
PharmacoGx SB590885

External IDs

DatabaseIdentifier
Smiles: CN(C)CCOC1=CC=C(C=C1)C2=NC(=C3C=CC4=C(CCC4=C3)N=O)C(=C5C=CNC=C5)N2
Inchikey: DPCXEUSDRQOOGZ-QLYXXIJNSA-N
Pubchem: 11316960

Annotated Targets

BRAF

Cell lines tested with SB590885

874 cell lines have been tested with this compound, using data from 1 dataset(s).
MCC26 skin GDSC10001
QIMR-WIL haematopoietic and lymphoid tissue GDSC10001
SK-N-AS autonomic ganglia GDSC10001
CPC-N lung GDSC10001
SK-MEL-5 skin GDSC10001
GCIY stomach GDSC10001
SUP-HD1 haematopoietic and lymphoid tissue GDSC10001
JEG-3 placenta GDSC10001
NB17 autonomic ganglia GDSC10001
Calu-3 lung GDSC10001
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Top molecular features associated with response to SB590885


Feature TypeStandardized
Nominal ANOVA
mRNA GAPDHS GDSC1000 AAC 0.32 3e-21
mRNA DCT GDSC1000 AAC 0.35 7e-17
mRNA CPN1 GDSC1000 AAC 0.35 1e-15
mRNA MMP8 GDSC1000 AAC 0.31 7e-15
mRNA TRIM51 GDSC1000 AAC 0.31 1e-13
mRNA PRDM7 GDSC1000 AAC 0.27 1e-13
mRNA TRIM63 GDSC1000 AAC 0.31 3e-13
mRNA MLANA GDSC1000 AAC 0.31 5e-13
mRNA PLP1 GDSC1000 AAC 0.35 7e-13
mRNA BIRC7 GDSC1000 AAC 0.24 5e-12
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