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SB-431542

Synonyms

SourcesNames Used
CTRPv2SB-431542
PharmacoGx SB-431542

External IDs

DatabaseIdentifier
Smiles: NC(=O)c1ccc(cc1)c2nc(c([nH]2)c3ccccn3)c4ccc5OCOc5c4
Pubchem: 4521392

Annotated Targets

ACVR1C, TGFBR1

Cell lines tested with SB-431542

823 cell lines have been tested with this compound, using data from 1 dataset(s).
A549 lung CTRPv23
DU-145 prostate CTRPv22
AsPC-1 pancreas CTRPv22
NCI-H1869 lung CTRPv22
CCF-STTG1 central nervous system CTRPv22
OAW-28 ovary CTRPv22
HeLa cervix CTRPv22
LOXIMVI haematopoietic and lymphoid tissue CTRPv22
NCI-H520 lung CTRPv22
MKN74 stomach CTRPv22
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Top molecular features associated with response to SB-431542


Feature TypeStandardized
Nominal ANOVA
mRNA LHCGR CTRPv2 AAC 0.27 1e-13
mRNA RP11-310N16.1 CTRPv2 AAC 0.26 2e-12
mRNA SLC26A5 CTRPv2 AAC 0.25 2e-11
mRNA ENPP2 CTRPv2 AAC 0.23 8e-10
mRNA GALNTL5 CTRPv2 AAC 0.22 2e-09
mRNA MEI4 CTRPv2 AAC 0.21 4e-09
mRNA SYT11 CTRPv2 AAC 0.26 5e-09
mRNA MS4A18 CTRPv2 AAC 0.22 8e-09
mRNA CYP2A13 CTRPv2 AAC 0.23 8e-09
mRNA SLC5A7 CTRPv2 AAC 0.21 1e-08
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