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SB 216763

Synonyms

SourcesNames Used
GDSC1000SB 216763
PharmacoGx SB 216763

External IDs

DatabaseIdentifier
Smiles: Cn1cc(C2=C(C(=O)NC2=O)c3ccc(Cl)cc3Cl)c4ccccc14
Pubchem: 176158

Annotated Targets

CCNA2, CDK2, GSK3A, GSK3B

Cell lines tested with SB 216763

787 cell lines have been tested with this compound, using data from 1 dataset(s).
TGBC1TKB biliary tract GDSC10001
NCI-H3122 lung GDSC10001
SW620 large intestine GDSC10001
NB17 autonomic ganglia GDSC10001
NB6 autonomic ganglia GDSC10001
COR-L88 lung GDSC10001
CAL-27 upper aerodigestive tract GDSC10001
T84 large intestine GDSC10001
HA7-RCC kidney GDSC10001
SK-OV-3 ovary GDSC10001
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Top molecular features associated with response to SB 216763


Feature TypeStandardized
Nominal ANOVA
mRNA CNTD2 GDSC1000 AAC -0.17 1e-05
mRNA HSPG2 GDSC1000 AAC 0.19 2e-05
mRNA FLNB GDSC1000 AAC 0.2 2e-05
mRNA GGCX GDSC1000 AAC 0.19 4e-05
mRNA ADAMTS9 GDSC1000 AAC 0.17 4e-05
mRNA CRHR1 GDSC1000 AAC -0.15 4e-05
mRNA TIFAB GDSC1000 AAC 0.15 5e-05
mRNA LZTR1 GDSC1000 AAC 0.15 9e-05
mRNA RBM26 GDSC1000 AAC -0.16 0.0001
mRNA TMEM233 GDSC1000 AAC 0.15 0.0001
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