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Salubrinal

Synonyms

SourcesNames Used
GDSC1000Salubrinal
PharmacoGx Salubrinal

External IDs

DatabaseIdentifier
Smiles: C1=CC=C(C=C1)C=CC(=O)NC(C(Cl)(Cl)Cl)NC(=S)NC2=CC=CC3=C2N=CC=C3
Inchikey: LCOIAYJMPKXARU-VAWYXSNFSA-N
Pubchem: 5717801

Annotated Targets

EIF2S1

Cell lines tested with Salubrinal

424 cell lines have been tested with this compound, using data from 1 dataset(s).
DMS-153 lung GDSC10001
ES5 bone GDSC10001
NCI-H1355 lung GDSC10001
SNU-C1 large intestine GDSC10001
EC-GI-10 oesophagus GDSC10001
MONO-MAC-6 haematopoietic and lymphoid tissue GDSC10001
EW-16 bone GDSC10001
COLO-320-HSR large intestine GDSC10001
BB65-RCC kidney GDSC10001
KMS-12-BM haematopoietic and lymphoid tissue GDSC10001
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Top molecular features associated with response to Salubrinal


Feature TypeStandardized
Nominal ANOVA
mRNA HPD GDSC1000 AAC 0.27 1e-07
mRNA BEX3 GDSC1000 AAC -0.31 4e-06
mRNA DNHD1 GDSC1000 AAC 0.25 5e-06
mRNA DGKD GDSC1000 AAC 0.23 1e-05
mRNA RYK GDSC1000 AAC -0.25 2e-05
mRNA GPD1 GDSC1000 AAC 0.21 3e-05
mRNA CHST15 GDSC1000 AAC 0.21 6e-05
mRNA RABGAP1L GDSC1000 AAC 0.25 6e-05
mRNA LRIT1 GDSC1000 AAC 0.2 0.0001
mRNA GATA2 GDSC1000 AAC -0.22 0.0001
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