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regorafenib

Synonyms

SourcesNames Used
CTRPv2regorafenib
PharmacoGx regorafenib

External IDs

DatabaseIdentifier
Pubchem: 11167602

Annotated Targets

FRK, DDR2, MAPK11, KIT, BRAF, TEK, ABL1, EPHA2, FGFR1, FGFR2, FLT1, FLT4, KDR, NTRK1, PDGFRA, PDGFRB, RAF1, RET

Cell lines tested with regorafenib

804 cell lines have been tested with this compound, using data from 1 dataset(s).
A549 lung CTRPv23
DU-145 prostate CTRPv22
AsPC-1 pancreas CTRPv22
NCI-H1869 lung CTRPv22
CCF-STTG1 central nervous system CTRPv22
OAW-28 ovary CTRPv22
HeLa cervix CTRPv22
NCI-H520 lung CTRPv22
MKN74 stomach CTRPv22
IGROV-1 ovary CTRPv22
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Top molecular features associated with response to regorafenib


Feature TypeStandardized
Nominal ANOVA
mRNA GOLGA8M CTRPv2 AAC 0.39 5e-29
mRNA GOLGA8J CTRPv2 AAC 0.38 7e-26
mRNA PRSS57 CTRPv2 AAC 0.37 6e-24
mRNA GOLGA8H CTRPv2 AAC 0.33 3e-19
mRNA GOLGA8T CTRPv2 AAC 0.33 1e-18
mRNA OR2B11 CTRPv2 AAC 0.32 2e-18
mRNA ITGAL CTRPv2 AAC 0.34 8e-17
mRNA GOLGA8Q CTRPv2 AAC 0.31 3e-16
mRNA PLPPR3 CTRPv2 AAC 0.3 5e-16
mRNA GOLGA8N CTRPv2 AAC 0.3 7e-16
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