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AZD8055

Synonyms

SourcesNames Used
GDSC1000, CTRPv2AZD8055
PharmacoGx AZD8055

External IDs

DatabaseIdentifier
Smiles: CC1COCCN1C2=NC(=NC3=C2C=CC(=N3)C4=CC(=C(C=C4)OC)CO)N5CCOCC5C
Inchikey: KVLFRAWTRWDEDF-IRXDYDNUSA-N
Pubchem: 25262965

Annotated Targets

MTOR

Cell lines tested with AZD8055

1258 cell lines have been tested with this compound, using data from 2 dataset(s).
A549 lung GDSC1000, CTRPv24
HeLa cervix GDSC1000, CTRPv23
NCI-H460 lung GDSC1000, CTRPv23
NCI-H1869 lung GDSC1000, CTRPv23
OAW-28 ovary GDSC1000, CTRPv23
IGROV-1 ovary GDSC1000, CTRPv23
LOXIMVI haematopoietic and lymphoid tissue GDSC1000, CTRPv23
CCF-STTG1 central nervous system GDSC1000, CTRPv23
DU-145 prostate GDSC1000, CTRPv23
SUIT-2 pancreas GDSC1000, CTRPv23
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Top molecular features associated with response to AZD8055


Feature TypeStandardized
Nominal ANOVA
mRNA RPL13 GDSC1000 AAC 0.18 8e-08
mRNA TOR3A CTRPv2 AAC 0.18 2e-06
mRNA RP4-583P15.14 CTRPv2 AAC 0.17 3e-06
mRNA GNAQ CTRPv2 AAC -0.16 4e-06
mRNA CAPG CTRPv2 AAC -0.16 5e-06
mRNA PRDM1 CTRPv2 AAC 0.17 6e-06
mRNA RNF122 CTRPv2 AAC 0.17 6e-06
mRNA LIME1 CTRPv2 AAC 0.16 6e-06
mRNA ASUN GDSC1000 AAC 0.15 7e-06
mRNA NCKAP1 GDSC1000 AAC -0.3 7e-06
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