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QS11

Synonyms

SourcesNames Used
GDSC1000QS11
CTRPv2QS-11
PharmacoGx QS11

External IDs

DatabaseIdentifier
Smiles: C1CC2=C(C1)C=C(C=C2)OC3=NC4=C(C(=N3)NC(CC5=CC=CC=C5)CO)N=CN4CC6=CC=C(C=C6)C7=CC=CC=C7
Inchikey: DOKZLKDGUQWMSX-HKBQPEDESA-N
Pubchem: 42623900

Annotated Targets

ARFGAP1

Cell lines tested with QS11

1016 cell lines have been tested with this compound, using data from 2 dataset(s).
NCI-H1299 lung GDSC1000, CTRPv23
SUIT-2 pancreas GDSC1000, CTRPv23
AGS stomach GDSC1000, CTRPv22
NCI-H1734 lung GDSC1000, CTRPv22
CAL-62 thyroid GDSC1000, CTRPv22
HCC1806 breast GDSC1000, CTRPv22
NCI-H28 pleura GDSC1000, CTRPv22
OVISE ovary GDSC1000, CTRPv22
CAL-29 urinary tract GDSC1000, CTRPv22
LAMA-84 haematopoietic and lymphoid tissue GDSC1000, CTRPv22
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Top molecular features associated with response to QS11


Feature TypeStandardized
Nominal ANOVA
mRNA POGZ GDSC1000 AAC 0.18 1e-06
mRNA CYTH2 GDSC1000 AAC 0.17 2e-06
mRNA ZKSCAN4 CTRPv2 AAC 0.4 3e-06
mRNA PBRM1 GDSC1000 AAC 0.19 3e-06
mRNA CDC14B GDSC1000 AAC -0.19 8e-06
mRNA C9orf40 GDSC1000 AAC 0.17 8e-06
mRNA ILDR1 GDSC1000 AAC -0.16 1e-05
mRNA TMEM127 GDSC1000 AAC -0.16 1e-05
mRNA LBX1 GDSC1000 AAC 0.15 1e-05
mRNA IARS GDSC1000 AAC 0.15 2e-05
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