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PX-12

Synonyms

SourcesNames Used
CTRPv2PX-12
PharmacoGx PX-12

External IDs

DatabaseIdentifier
Smiles: CCC(C)SSC1=NC=CN1
Inchikey: BPBPYQWMFCTCNG-UHFFFAOYSA-N
Pubchem: 219104

Annotated Targets

TXN, TXNRD1

Cell lines tested with PX-12

814 cell lines have been tested with this compound, using data from 1 dataset(s).
A549 lung CTRPv23
DU-145 prostate CTRPv22
AsPC-1 pancreas CTRPv22
NCI-H1869 lung CTRPv22
CCF-STTG1 central nervous system CTRPv22
OAW-28 ovary CTRPv22
HeLa cervix CTRPv22
LOXIMVI haematopoietic and lymphoid tissue CTRPv22
NCI-H520 lung CTRPv22
MKN74 stomach CTRPv22
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Top molecular features associated with response to PX-12


Feature TypeStandardized
Nominal ANOVA
mRNA MEX3A CTRPv2 AAC 0.31 3e-20
mRNA MBTD1 CTRPv2 AAC 0.31 3e-20
mRNA IDH2 CTRPv2 AAC 0.27 5e-20
mRNA HCFC1 CTRPv2 AAC 0.3 7e-20
mRNA TMSB15A CTRPv2 AAC 0.26 1e-18
mRNA ZNF253 CTRPv2 AAC 0.26 2e-18
mRNA FAM117B CTRPv2 AAC 0.26 3e-18
mRNA SLC7A11 CTRPv2 AAC -0.25 4e-18
mRNA RSBN1L CTRPv2 AAC 0.27 6e-18
mRNA YPEL1 CTRPv2 AAC 0.26 2e-17
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