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SourcesNames Used
GDSC1000, CTRPv2piperlongumine
PharmacoGx piperlongumine

External IDs

Smiles: COC1=CC(=CC(=C1OC)OC)C=CC(=O)N2CCC=CC2=O
Pubchem: 637858

Cell lines tested with piperlongumine

1264 cell lines have been tested with this compound, using data from 2 dataset(s).
A549 lung GDSC1000, CTRPv24
LOXIMVI haematopoietic and lymphoid tissue GDSC1000, CTRPv23
NCI-H460 lung GDSC1000, CTRPv23
NCI-H1869 lung GDSC1000, CTRPv23
OAW-28 ovary GDSC1000, CTRPv23
CAL-51 breast GDSC1000, CTRPv23
HeLa cervix GDSC1000, CTRPv23
IGROV-1 ovary GDSC1000, CTRPv23
NCI-H1299 lung GDSC1000, CTRPv23
CCF-STTG1 central nervous system GDSC1000, CTRPv23
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Top molecular features associated with response to piperlongumine

Feature TypeStandardized
Nominal ANOVA
mRNA SLC7A11 CTRPv2 AAC -0.22 1e-11
mRNA NQO1 CTRPv2 AAC -0.23 6e-11
mRNA TXNRD1 CTRPv2 AAC -0.24 7e-11
mRNA PGD CTRPv2 AAC -0.21 1e-10
mRNA SRXN1 CTRPv2 AAC -0.21 3e-10
mRNA RP5-850E9.3 CTRPv2 AAC -0.21 3e-10
mRNA PTGR1 CTRPv2 AAC -0.21 5e-10
mRNA TRIM16L CTRPv2 AAC -0.21 6e-10
mRNA FTL CTRPv2 AAC -0.21 1e-09
mRNA TALDO1 CTRPv2 AAC -0.19 1e-09
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