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phenformin

Synonyms

SourcesNames Used
GDSC1000Phenformin
PharmacoGx phenformin

External IDs

DatabaseIdentifier
Smiles: NC(=N)NC(=N)NCCc1ccccc1
Inchikey: ICFJFFQQTFMIBG-UHFFFAOYSA-N
Pubchem: 8249

Annotated Targets

KCNJ8, PRKAA1

Cell lines tested with phenformin

975 cell lines have been tested with this compound, using data from 1 dataset(s).
SN12C kidney GDSC10001
AM-38 central nervous system GDSC10001
CCRF-CEM haematopoietic and lymphoid tissue GDSC10001
OCI-AML5 haematopoietic and lymphoid tissue GDSC10001
IST-SL2 lung GDSC10001
MDA-MB-231 breast GDSC10001
MFE-280 endometrium GDSC10001
FU-OV-1 ovary GDSC10001
NCI-H322M lung GDSC10001
NB(TU)1-10 neuroblastoma GDSC10001
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Top molecular features associated with response to phenformin


Feature TypeStandardized
Nominal ANOVA
mRNA C15orf61 GDSC1000 AAC 0.18 1e-08
mRNA NABP1 GDSC1000 AAC -0.18 4e-08
mRNA PROCA1 GDSC1000 AAC 0.16 1e-07
mRNA STAT1 GDSC1000 AAC -0.16 2e-07
mRNA PHF14 GDSC1000 AAC 0.17 2e-07
mRNA ZNFX1 GDSC1000 AAC -0.17 2e-07
mRNA C20orf96 GDSC1000 AAC 0.16 3e-07
mRNA MGLL GDSC1000 AAC -0.17 4e-07
mRNA SPATS2L GDSC1000 AAC -0.19 4e-07
mRNA KIF1BP GDSC1000 AAC -0.19 4e-07
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