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PHA-793887

Synonyms

SourcesNames Used
GDSC1000, CTRPv2PHA-793887
PharmacoGx PHA-793887

External IDs

DatabaseIdentifier
Smiles: CC(C)CC(=O)Nc1n[nH]c2c1CN(C(=O)C1CCN(C)CC1)C2(C)C
Pubchem: 46191454

Annotated Targets

CDK14, CDK1, CDK2, CDK4, CDK5, CDK7, CDK9

Cell lines tested with PHA-793887

1284 cell lines have been tested with this compound, using data from 2 dataset(s).
A549 lung CTRPv23
NCI-H460 lung GDSC1000, CTRPv23
LOXIMVI haematopoietic and lymphoid tissue GDSC1000, CTRPv23
OAW-28 ovary GDSC1000, CTRPv23
NCI-H1299 lung GDSC1000, CTRPv23
HeLa cervix GDSC1000, CTRPv23
CAL-51 breast GDSC1000, CTRPv23
NCI-H1869 lung GDSC1000, CTRPv23
CCF-STTG1 central nervous system GDSC1000, CTRPv23
DU-145 prostate GDSC1000, CTRPv23
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Top molecular features associated with response to PHA-793887


Feature TypeStandardized
Nominal ANOVA
mRNA SAFB GDSC1000 AAC 0.26 5e-14
mRNA AMER2 GDSC1000 AAC 0.23 6e-14
mRNA CTSA GDSC1000 AAC -0.24 2e-13
mRNA RPRD2 GDSC1000 AAC 0.21 3e-12
mRNA MEX3A GDSC1000 AAC 0.22 1e-11
mRNA PRPF4B GDSC1000 AAC 0.2 2e-11
mRNA ZNF232 GDSC1000 AAC 0.19 4e-11
mRNA SDC4 GDSC1000 AAC -0.26 6e-11
mRNA RPAIN GDSC1000 AAC 0.19 1e-10
mRNA RRAS GDSC1000 AAC -0.23 2e-10
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