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SourcesNames Used
PharmacoGx PF-562271

External IDs

Smiles: CN(C1=C(C=CC=N1)CNC2=NC(=NC=C2C(F)(F)F)NC3=CC4=C(C=C3)NC(=O)C4)S(=O)(=O)C
Pubchem: 11713159

Annotated Targets


Cell lines tested with PF-562271

941 cell lines have been tested with this compound, using data from 1 dataset(s).
HCC2157 breast GDSC10001
LB373-MEL-D skin GDSC10001
IMR-5 autonomic ganglia GDSC10001
LOXIMVI haematopoietic and lymphoid tissue GDSC10001
KLE endometrium GDSC10001
Mewo skin GDSC10001
BICR 31 upper aerodigestive tract GDSC10001
SBC-1 lung GDSC10001
HOP-62 lung GDSC10001
SK-MEL-28 haematopoietic and lymphoid tissue GDSC10001
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Top molecular features associated with response to PF-562271

Feature TypeStandardized
Nominal ANOVA
mRNA SMAD3 GDSC1000 AAC 0.26 5e-12
mRNA GPX8 GDSC1000 AAC 0.31 2e-11
mRNA VEGFC GDSC1000 AAC 0.26 1e-10
mRNA MYOF GDSC1000 AAC 0.29 3e-10
mRNA PTRF GDSC1000 AAC 0.26 3e-10
mRNA PLIN3 GDSC1000 AAC 0.22 4e-10
mRNA EPB41 GDSC1000 AAC -0.23 7e-10
mRNA TNFRSF12A GDSC1000 AAC 0.29 1e-09
mRNA TNFRSF1A GDSC1000 AAC 0.22 2e-09
mRNA GBE1 GDSC1000 AAC 0.22 3e-09
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