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PF-4708671

Synonyms

SourcesNames Used
GDSC1000PF-4708671
PharmacoGx PF-4708671

External IDs

DatabaseIdentifier
Smiles: CCC1=CN=CN=C1N2CCN(CC2)CC3=NC4=C(N3)C=C(C=C4)C(F)(F)F
Inchikey: FBLPQCAQRNSVHB-UHFFFAOYSA-N
Pubchem: 51371303

Annotated Targets

RPS6KB1

Cell lines tested with PF-4708671

965 cell lines have been tested with this compound, using data from 1 dataset(s).
ACHN kidney GDSC10001
CPC-N lung GDSC10001
S-117 soft tissue GDSC10001
AN3-CA endometrium GDSC10001
Geo large intestine GDSC10001
KMOE-2 haematopoietic and lymphoid tissue GDSC10001
WM239A skin GDSC10001
BE-13 haematopoietic and lymphoid tissue GDSC10001
LC-1-sq lung GDSC10001
COR-L279 lung GDSC10001
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Top molecular features associated with response to PF-4708671


Feature TypeStandardized
Nominal ANOVA
mRNA LGALS2 GDSC1000 AAC 0.14 8e-05
mRNA ATPAF1 GDSC1000 AAC -0.13 0.0001
mRNA ZMAT2 GDSC1000 AAC -0.12 0.0002
mRNA LRRC31 GDSC1000 AAC 0.13 0.0003
mRNA CCR8 GDSC1000 AAC 0.12 0.0003
mRNA A4GNT GDSC1000 AAC -0.12 0.0003
mRNA FFAR4 GDSC1000 AAC 0.12 0.0005
mRNA RPGR GDSC1000 AAC 0.12 0.0005
mRNA TRNP1 GDSC1000 AAC 0.14 0.0007
mRNA BOD1 GDSC1000 AAC -0.15 0.0008
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