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SourcesNames Used
PharmacoGx PD318088

External IDs

Pubchem: 10231331

Annotated Targets


Cell lines tested with PD318088

854 cell lines have been tested with this compound, using data from 1 dataset(s).
A549 lung CTRPv23
DU-145 prostate CTRPv22
AsPC-1 pancreas CTRPv22
NCI-H1869 lung CTRPv22
CCF-STTG1 central nervous system CTRPv22
OAW-28 ovary CTRPv22
HeLa cervix CTRPv22
LOXIMVI haematopoietic and lymphoid tissue CTRPv22
NCI-H520 lung CTRPv22
MKN74 stomach CTRPv22
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Top molecular features associated with response to PD318088

Feature TypeStandardized
Nominal ANOVA
mRNA SPRY2 CTRPv2 AAC 0.33 4e-19
mRNA LYST CTRPv2 AAC 0.28 7e-15
mRNA SPRY4 CTRPv2 AAC 0.27 3e-13
mRNA ZFP36L2 CTRPv2 AAC 0.27 5e-13
mRNA HSD17B11 CTRPv2 AAC 0.26 6e-13
mRNA IRF2BP2 CTRPv2 AAC 0.25 2e-12
mRNA ARAP3 CTRPv2 AAC 0.26 3e-12
mRNA GKAP1 CTRPv2 AAC -0.25 4e-12
mRNA NLRP3 CTRPv2 AAC 0.24 5e-12
mRNA ACY1 CTRPv2 AAC 0.25 6e-12
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