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PD173074

Synonyms

SourcesNames Used
GDSC1000PD-173074
PharmacoGx PD173074

External IDs

DatabaseIdentifier
Smiles: CCN(CC)CCCCNC1=NC2=NC(=C(C=C2C=N1)C3=CC(=CC(=C3)OC)OC)NC(=O)NC(C)(C)C
Inchikey: DXCUKNQANPLTEJ-UHFFFAOYSA-N
Pubchem: 1401

Annotated Targets

FGFR1, FGFR2, FGFR3, FGFR4, FLT1, FLT4, KDR, PDGFRA, PDGFRB

Cell lines tested with PD173074

890 cell lines have been tested with this compound, using data from 1 dataset(s).
SLVL haematopoietic and lymphoid tissue GDSC10001
NCI-H1703 lung GDSC10001
DEL haematopoietic and lymphoid tissue GDSC10001
CPC-N lung GDSC10001
NCI-H510A lung GDSC10001
BB49-HNC upper aerodigestive tract GDSC10001
D-336MG central nervous system GDSC10001
JHU-022 head and neck GDSC10001
NH-12 autonomic ganglia GDSC10001
K2 thyroid GDSC10001
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Top molecular features associated with response to PD173074


Feature TypeStandardized
Nominal ANOVA
mRNA FGFR2 GDSC1000 AAC 0.29 4e-15
mRNA GALNT15 GDSC1000 AAC 0.21 6e-09
mRNA RBPMS2 GDSC1000 AAC 0.2 4e-08
mRNA HAS1 GDSC1000 AAC 0.18 2e-07
mRNA B3GNT6 GDSC1000 AAC 0.18 2e-07
mRNA POLG GDSC1000 AAC 0.16 4e-06
mRNA KAT2A GDSC1000 AAC 0.16 4e-06
mRNA DET1 GDSC1000 AAC 0.16 7e-06
mRNA FSHB GDSC1000 AAC 0.15 1e-05
mRNA XAB2 GDSC1000 AAC 0.16 1e-05
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