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PD-0332991

Synonyms

SourcesNames Used
CCLE, GDSC1000PD-0332991
FIMMPalbociclib
PharmacoGx PD-0332991

External IDs

DatabaseIdentifier
Smiles: CC1=C(C(=O)N(C2=NC(=NC=C12)NC3=NC=C(C=C3)N4CCNCC4)C5CCCC5)C(=O)C
Inchikey: AHJRHEGDXFFMBM-UHFFFAOYSA-N
Pubchem: 5330286

Cell lines tested with PD-0332991

1033 cell lines have been tested with this compound, using data from 3 dataset(s).
T47D breast CCLE, GDSC1000, FIMM3
SK-OV-3 ovary CCLE, GDSC1000, FIMM3
PC-3 prostate CCLE, GDSC1000, FIMM3
OVCAR-8 ovary CCLE, GDSC1000, FIMM3
OVCAR-4 ovary CCLE, GDSC1000, FIMM3
OV-90 ovary CCLE, GDSC1000, FIMM3
OCI-AML5 haematopoietic and lymphoid tissue CCLE, GDSC1000, FIMM3
OCI-AML2 haematopoietic and lymphoid tissue CCLE, GDSC1000, FIMM3
OVCAR-3 ovary CCLE, GDSC1000, FIMM3
MDA-MB-468 breast CCLE, GDSC1000, FIMM3
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Top molecular features associated with response to PD-0332991


Feature TypeStandardized
Nominal ANOVA
mRNA CDKN2A GDSC1000 AAC -0.29 2e-17
mRNA GNA15 GDSC1000 AAC 0.32 3e-16
mRNA B3GNTL1 GDSC1000 AAC 0.25 4e-13
mRNA SPNS3 GDSC1000 AAC 0.26 6e-12
mRNA CCNE1 GDSC1000 AAC -0.24 1e-11
mRNA RB1 GDSC1000 AAC 0.25 9e-11
mRNA CMTM3 GDSC1000 AAC 0.24 3e-10
mRNA CNEP1R1 GDSC1000 AAC 0.22 3e-10
mRNA ERLIN1 GDSC1000 AAC 0.21 1e-09
mRNA CD96 GDSC1000 AAC 0.22 2e-09
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