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Pazopanib

Synonyms

SourcesNames Used
GDSC1000, FIMMPazopanib
PharmacoGx Pazopanib

External IDs

DatabaseIdentifier
Smiles: CC1=C(C=C(C=C1)NC2=NC=CC(=N2)N(C)C3=CC4=NN(C(=C4C=C3)C)C)S(=O)(=O)N.Cl
Inchikey: MQHIQUBXFFAOMK-UHFFFAOYSA-N
Pubchem: 11525740

Cell lines tested with Pazopanib

940 cell lines have been tested with this compound, using data from 2 dataset(s).
ML-2 haematopoietic and lymphoid tissue GDSC1000, FIMM2
RMG-I ovary GDSC1000, FIMM2
MDA-MB-453 breast GDSC1000, FIMM2
RPMI-8226 haematopoietic and lymphoid tissue GDSC1000, FIMM2
MDA-MB-231 breast GDSC1000, FIMM2
PC-3 prostate GDSC1000, FIMM2
OV-90 ovary GDSC1000, FIMM2
THP-1 haematopoietic and lymphoid tissue GDSC1000, FIMM2
K-562 haematopoietic and lymphoid tissue GDSC1000, FIMM2
DU-4475 breast GDSC1000, FIMM2
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Top molecular features associated with response to Pazopanib


Feature TypeStandardized
Nominal ANOVA
mRNA PDGFRA GDSC1000 AAC 0.26 5e-12
mRNA MRC2 GDSC1000 AAC 0.23 1e-08
mRNA DLK1 FIMM AAC 0.92 1e-08
mRNA CSF1R GDSC1000 AAC 0.19 3e-08
mRNA P2RX6 GDSC1000 AAC 0.18 1e-07
mRNA LATS2 GDSC1000 AAC 0.2 2e-07
mRNA SLAIN1 GDSC1000 AAC -0.21 2e-07
mRNA LILRA1 GDSC1000 AAC 0.18 3e-07
mRNA SYNC GDSC1000 AAC 0.2 3e-07
mRNA MSRB3 GDSC1000 AAC 0.2 4e-07
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