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pazopanib

Synonyms

SourcesNames Used
CTRPv2pazopanib
PharmacoGx pazopanib

External IDs

DatabaseIdentifier
Smiles: CC1=C(C=C(C=C1)NC2=NC=CC(=N2)N(C)C3=CC4=NN(C(=C4C=C3)C)C)S(=O)(=O)N
Inchikey: CUIHSIWYWATEQL-UHFFFAOYSA-N
Pubchem: 10113978

Annotated Targets

FGFR3, CSF1R, LCK, KIT, FGF1, FGFR1, FLT1, FLT4, ITK, KDR, PDGFRA, PDGFRB, SH2B3, FLT3

FDA Approval Status

Approved
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Top molecular features associated with response to pazopanib


Feature TypeStandardized
Nominal ANOVA
mRNA GDSC1000 pan-cancer AAC 0.31 2e-09
mRNA GDSC1000 pan-cancer AAC 0.2 3e-08
mRNA GDSC1000 pan-cancer AAC 0.18 5e-08
mRNA GDSC1000 pan-cancer AAC 0.3 9e-08
mRNA GDSC1000 pan-cancer AAC 0.18 2e-07
mRNA GDSC1000 pan-cancer AAC 0.18 2e-07
mRNA GDSC1000 pan-cancer AAC 0.16 1e-06
mRNA CTRPv2 pan-cancer AAC 0.17 2e-06
mRNA CTRPv2 pan-cancer AAC 0.17 6e-06
mRNA CTRPv2 pan-cancer AAC 0.17 2e-05
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