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AZD0530

Synonyms

SourcesNames Used
CCLEAZD0530
GDSC1000, FIMMSaracatinib
CTRPv2saracatinib
PharmacoGx AZD0530

External IDs

DatabaseIdentifier
Smiles: CN1CCN(CC1)CCOC2=CC(=C3C(=C2)N=CN=C3NC4=C(C=CC5=C4OCO5)Cl)OC6CCOCC6
Inchikey: OUKYUETWWIPKQR-UHFFFAOYSA-N
Pubchem: 10302451

Cell lines tested with AZD0530

1134 cell lines have been tested with this compound, using data from 4 dataset(s).
SIG-M5 haematopoietic and lymphoid tissue CCLE, GDSC1000, FIMM, CTRPv24
OVCAR-4 ovary CCLE, GDSC1000, FIMM, CTRPv24
OCI-AML5 haematopoietic and lymphoid tissue CCLE, GDSC1000, FIMM, CTRPv24
OCI-AML2 haematopoietic and lymphoid tissue CCLE, GDSC1000, FIMM, CTRPv24
NCI-H1869 lung CCLE, GDSC1000, CTRPv24
NCI-H1299 lung CCLE, GDSC1000, CTRPv24
LOXIMVI haematopoietic and lymphoid tissue CCLE, GDSC1000, CTRPv24
IGROV-1 ovary CCLE, FIMM, CTRPv24
ES-2 ovary CCLE, GDSC1000, FIMM, CTRPv24
BT-474 breast CCLE, GDSC1000, FIMM, CTRPv24
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Top molecular features associated with response to AZD0530


Feature TypeStandardized
Nominal ANOVA
mRNA PIM1 CTRPv2 AAC 0.31 2e-16
mRNA SLC6A19 CTRPv2 AAC 0.25 1e-12
mRNA CISH CTRPv2 AAC 0.25 5e-12
mRNA ANK1 CTRPv2 AAC 0.24 7e-12
mRNA ACSM1 CTRPv2 AAC 0.22 7e-10
mRNA MRPS14 CTRPv2 AAC -0.23 1e-09
mRNA CD69 CTRPv2 AAC 0.23 2e-09
mRNA SRM CTRPv2 AAC -0.23 5e-09
mRNA UBE2Q1 CTRPv2 AAC -0.21 2e-08
mRNA THEM4 CCLE AAC -0.28 2e-08
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