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AZD-7545

Synonyms

SourcesNames Used
CTRPv2AZD7545
PharmacoGx AZD-7545

External IDs

DatabaseIdentifier
Smiles: CC(C(=O)NC1=C(C=C(C=C1)S(=O)(=O)C2=CC=C(C=C2)C(=O)N(C)C)Cl)(C(F)(F)F)O
Inchikey: DTDZLJHKVNTQGZ-GOSISDBHSA-N
Pubchem: 16741245

Annotated Targets

PDK1, PDK2

Cell lines tested with AZD-7545

829 cell lines have been tested with this compound, using data from 1 dataset(s).
CAS-1 central nervous system CTRPv21
KPL-1 breast CTRPv21
MKN1 stomach CTRPv21
CAL-120 breast CTRPv21
HuCCT1 biliary tract CTRPv21
NMC-G1 central nervous system CTRPv21
ALL-SIL haematopoietic and lymphoid tissue CTRPv21
HDQ-P1 breast CTRPv21
SNU-489 central nervous system CTRPv21
SNU-626 central nervous system CTRPv21
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Top molecular features associated with response to AZD-7545


Feature TypeStandardized
Nominal ANOVA
mRNA ZNF540 CTRPv2 AAC 0.16 1e-05
mRNA LRRC58 CTRPv2 AAC 0.16 1e-05
mRNA COA7 CTRPv2 AAC 0.16 1e-05
mRNA TMX1 CTRPv2 AAC 0.16 2e-05
mRNA NOLC1 CTRPv2 AAC 0.16 2e-05
mRNA PCDHGB4 CTRPv2 AAC -0.19 2e-05
mRNA CYBRD1 CTRPv2 AAC -0.17 2e-05
mRNA PCDHGB5 CTRPv2 AAC -0.19 3e-05
mRNA ATXN7L2 CTRPv2 AAC 0.16 3e-05
mRNA PCDHGB7 CTRPv2 AAC -0.19 3e-05
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