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AZD-7545

Synonyms

SourcesNames Used
CTRPv2AZD7545
PharmacoGx AZD-7545

External IDs

DatabaseIdentifier
Smiles: CC(C(=O)NC1=C(C=C(C=C1)S(=O)(=O)C2=CC=C(C=C2)C(=O)N(C)C)Cl)(C(F)(F)F)O
Inchikey: DTDZLJHKVNTQGZ-GOSISDBHSA-N
Pubchem: 16741245

Annotated Targets

PDK1, PDK2

Cell lines tested with AZD-7545

829 cell lines have been tested with this compound, using data from 1 dataset(s).
CAS-1 central nervous system CTRPv21
KPL-1 breast CTRPv21
MKN1 stomach CTRPv21
CAL-120 breast CTRPv21
HuCCT1 biliary tract CTRPv21
NMC-G1 central nervous system CTRPv21
ALL-SIL haematopoietic and lymphoid tissue CTRPv21
HDQ-P1 breast CTRPv21
SNU-489 central nervous system CTRPv21
SNU-626 central nervous system CTRPv21
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Top molecular features associated with response to AZD-7545


Feature TypeStandardized
Nominal ANOVA
mRNA ACTL7A CTRPv2 AAC 0.17 3e-06
mRNA ZNF519 CTRPv2 AAC 0.18 4e-06
mRNA RPS5 CTRPv2 AAC 0.17 5e-06
mRNA ORC1 CTRPv2 AAC 0.19 6e-06
mRNA PHF7 CTRPv2 AAC 0.2 6e-06
mRNA PCGF6 CTRPv2 AAC 0.16 7e-06
mRNA TIMP2 CTRPv2 AAC -0.2 9e-06
mRNA NKG7 CTRPv2 AAC 0.17 9e-06
mRNA MAGI3 CTRPv2 AAC 0.18 9e-06
mRNA DSCC1 CTRPv2 AAC 0.16 9e-06
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