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SourcesNames Used
PharmacoGx AZD-7545

External IDs

Smiles: CC(C(=O)NC1=C(C=C(C=C1)S(=O)(=O)C2=CC=C(C=C2)C(=O)N(C)C)Cl)(C(F)(F)F)O
Pubchem: 16741245

Annotated Targets


Cell lines tested with AZD-7545

829 cell lines have been tested with this compound, using data from 1 dataset(s).
RH-41 soft tissue CTRPv21
WSU-DLCL2 haematopoietic and lymphoid tissue CTRPv21
23132-87 stomach CTRPv21
8305C thyroid CTRPv21
BHY upper aerodigestive tract CTRPv21
GSU stomach CTRPv21
JIMT-1 breast CTRPv21
KMRC-20 kidney CTRPv21
OUMS-23 large intestine CTRPv21
SNU-1076 upper aerodigestive tract CTRPv21
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Top molecular features associated with response to AZD-7545

Feature TypeStandardized
Nominal ANOVA
mRNA PRIM1 CTRPv2 AAC 0.21 5e-08
mRNA MAPK8 CTRPv2 AAC 0.2 6e-08
mRNA ZNF583 CTRPv2 AAC 0.19 9e-08
mRNA ZNF679 CTRPv2 AAC 0.18 2e-07
mRNA ZNF714 CTRPv2 AAC 0.18 6e-07
mRNA ARHGAP19 CTRPv2 AAC 0.22 1e-06
mRNA ARHGAP19-SLIT1 CTRPv2 AAC 0.21 1e-06
mRNA MIS18A CTRPv2 AAC 0.19 1e-06
mRNA PHGDH CTRPv2 AAC 0.18 1e-06
mRNA RP11-894J14.5 CTRPv2 AAC 0.19 2e-06
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