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SourcesNames Used
PharmacoGx pac-1

External IDs

Smiles: Oc1c(CC=C)cccc1C=NNC(=O)CN2CCN(Cc3ccccc3)CC2
Pubchem: 6851947

Annotated Targets


Cell lines tested with pac-1

1228 cell lines have been tested with this compound, using data from 2 dataset(s).
A549 lung CTRPv23
NCI-H460 lung GDSC1000, CTRPv23
A375 skin GDSC1000, CTRPv23
NCI-H1869 lung GDSC1000, CTRPv23
OAW-28 ovary GDSC1000, CTRPv23
NCI-H1299 lung GDSC1000, CTRPv23
SUIT-2 pancreas GDSC1000, CTRPv23
CCF-STTG1 central nervous system GDSC1000, CTRPv23
DU-145 prostate GDSC1000, CTRPv23
AsPC-1 pancreas GDSC1000, CTRPv23
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Top molecular features associated with response to pac-1

Feature TypeStandardized
Nominal ANOVA
mRNA ZNF669 CTRPv2 AAC 0.29 3e-15
mRNA RP11-15H20.8 CTRPv2 AAC 0.28 1e-14
mRNA CENPV CTRPv2 AAC 0.3 3e-14
mRNA CPSF6 CTRPv2 AAC 0.31 4e-14
mRNA ARHGEF7 CTRPv2 AAC 0.27 2e-13
mRNA MARCKSL1 CTRPv2 AAC 0.26 4e-13
mRNA FAM117B CTRPv2 AAC 0.27 5e-13
mRNA KIF1A CTRPv2 AAC 0.28 5e-13
mRNA CASP8AP2 CTRPv2 AAC 0.26 6e-13
mRNA HCFC1 CTRPv2 AAC 0.29 6e-13
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