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AZD-7545

Synonyms

SourcesNames Used
CTRPv2AZD7545
PharmacoGx AZD-7545

External IDs

DatabaseIdentifier
Smiles: CC(C(=O)NC1=C(C=C(C=C1)S(=O)(=O)C2=CC=C(C=C2)C(=O)N(C)C)Cl)(C(F)(F)F)O
Inchikey: DTDZLJHKVNTQGZ-GOSISDBHSA-N
Pubchem: 16741245

Annotated Targets

PDK1, PDK2

Cell lines tested with AZD-7545

829 cell lines have been tested with this compound, using data from 1 dataset(s).
A549 lung CTRPv23
DU-145 prostate CTRPv22
AsPC-1 pancreas CTRPv22
NCI-H1869 lung CTRPv22
CCF-STTG1 central nervous system CTRPv22
OAW-28 ovary CTRPv22
HeLa cervix CTRPv22
NCI-H520 lung CTRPv22
MKN74 stomach CTRPv22
IGROV-1 ovary CTRPv22
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Tissues tested with AZD-7545

25 tissues have been tested with this compound, using data from 1 dataset(s).
haematopoietic and lymphoid tissueCTRPv2154
lungCTRPv2146
central nervous systemCTRPv247
large intestineCTRPv246
N/ACTRPv244
skinCTRPv244
ovaryCTRPv241
pancreasCTRPv240
breastCTRPv236
stomachCTRPv233
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Download Data as CSV

Top molecular features associated with response to AZD-7545


Feature TypeStandardized
Nominal ANOVA
mRNA PRIM1 CTRPv2 AAC 0.21 5e-08
mRNA MAPK8 CTRPv2 AAC 0.2 6e-08
mRNA ZNF583 CTRPv2 AAC 0.19 9e-08
mRNA ZNF679 CTRPv2 AAC 0.18 2e-07
mRNA ZNF714 CTRPv2 AAC 0.18 6e-07
mRNA ARHGAP19 CTRPv2 AAC 0.22 1e-06
mRNA ARHGAP19-SLIT1 CTRPv2 AAC 0.21 1e-06
mRNA MIS18A CTRPv2 AAC 0.19 1e-06
mRNA PHGDH CTRPv2 AAC 0.18 1e-06
mRNA RP11-894J14.5 CTRPv2 AAC 0.19 2e-06
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