1. Home/
  2. Compounds/
  3. NVP-BEZ235

NVP-BEZ235

Synonyms

SourcesNames Used
GDSC1000, GRAYBEZ235
CTRPv2NVP-BEZ235
PharmacoGx NVP-BEZ235

External IDs

DatabaseIdentifier
Smiles: CC(C)(C#N)C1=CC=C(C=C1)N2C3=C4C=C(C=CC4=NC=C3N(C2=O)C)C5=CC6=CC=CC=C6N=C5
Inchikey: JOGKUKXHTYWRGZ-UHFFFAOYSA-N
Pubchem: 11977753

Annotated Targets

ATR, MTOR, PIK3CA, PIK3CD, PIK3CG, PIK3CB

Cell lines tested with NVP-BEZ235

1181 cell lines have been tested with this compound, using data from 3 dataset(s).
MDA-MB-361 breast GDSC1000, GRAY, CTRPv25
BT-474 breast GDSC1000, GRAY, CTRPv25
MDA-MB-415 breast GDSC1000, GRAY, CTRPv24
HCC1428 breast GDSC1000, GRAY, CTRPv24
MDA-MB-231 breast GDSC1000, GRAY, CTRPv24
BT-20 breast GDSC1000, GRAY, CTRPv24
Hs-578-T breast GDSC1000, GRAY, CTRPv24
MDA-MB-175-VII breast GRAY3
MX-1 breast GRAY3
ZR-75-1 breast GRAY, CTRPv23
Download CSV
Download Data as CSV

Top molecular features associated with response to NVP-BEZ235


Feature TypeStandardized
Nominal ANOVA
mRNA RRAS GDSC1000 AAC 0.28 8e-11
mRNA GPX8 GDSC1000 AAC 0.31 9e-11
mRNA AXL GDSC1000 AAC 0.26 4e-10
mRNA CHGA GDSC1000 AAC -0.26 8e-10
mRNA CELF4 GDSC1000 AAC -0.23 1e-09
mRNA PROCR GDSC1000 AAC 0.24 1e-09
mRNA LRRC8B GDSC1000 AAC -0.23 2e-09
mRNA GTF2E2 GDSC1000 AAC 0.2 3e-09
mRNA IKBIP GDSC1000 AAC 0.24 4e-09
mRNA GNG11 GDSC1000 AAC 0.24 4e-09
Download CSV