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NU-7441

Synonyms

SourcesNames Used
GDSC1000NU-7441
PharmacoGx NU-7441

External IDs

DatabaseIdentifier
Smiles: C1COCCN1C2=CC(=O)C3=C(O2)C(=CC=C3)C4=CC=CC5=C4SC6=CC=CC=C56
Inchikey: JAMULYFATHSZJM-UHFFFAOYSA-N
Pubchem: 11327430

Annotated Targets

PRKDC

Cell lines tested with NU-7441

889 cell lines have been tested with this compound, using data from 1 dataset(s).
RCM-1 large intestine GDSC10001
CAL-85-1 breast GDSC10001
T84 large intestine GDSC10001
P32-ISH haematopoietic and lymphoid tissue GDSC10001
SU-DHL-4 haematopoietic and lymphoid tissue GDSC10001
LNCaP-Clone-FGC prostate GDSC10001
WSU-NHL haematopoietic and lymphoid tissue GDSC10001
SNU-182 liver GDSC10001
Becker central nervous system GDSC10001
CAL-27 upper aerodigestive tract GDSC10001
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Top molecular features associated with response to NU-7441


Feature TypeStandardized
Nominal ANOVA
mRNA HIST1H2BB GDSC1000 AAC 0.17 2e-06
mRNA UBL4B GDSC1000 AAC -0.14 0.0001
mRNA MRO GDSC1000 AAC 0.14 0.0001
mRNA SCN8A GDSC1000 AAC -0.14 0.0001
mRNA PROSER2 GDSC1000 AAC 0.17 0.0001
mRNA SIGLEC9 GDSC1000 AAC 0.14 0.0001
mRNA APOOL GDSC1000 AAC -0.14 0.0001
mRNA TSPO GDSC1000 AAC 0.15 0.0002
mRNA DPEP3 GDSC1000 AAC 0.14 0.0002
mRNA FAM9B GDSC1000 AAC 0.13 0.0003
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