1. Home/
  2. Compounds/
  3. AZ628

AZ628

Synonyms

SourcesNames Used
GDSC1000AZ628
PharmacoGx AZ628

External IDs

DatabaseIdentifier
Smiles: CC1=C(C=C(C=C1)NC(=O)C2=CC(=CC=C2)C(C)(C)C#N)NC3=CC4=C(C=C3)N=CN(C4=O)C
Inchikey: ZGBGPEDJXCYQPH-UHFFFAOYSA-N
Pubchem: 11676786

Annotated Targets

BRAF, RAF1

Cell lines tested with AZ628

429 cell lines have been tested with this compound, using data from 1 dataset(s).
L-363 haematopoietic and lymphoid tissue GDSC10001
SU-DHL-6 haematopoietic and lymphoid tissue GDSC10001
JVM-3 haematopoietic and lymphoid tissue GDSC10001
L-428 haematopoietic and lymphoid tissue GDSC10001
ACN autonomic ganglia GDSC10001
D-542MG central nervous system GDSC10001
BB49-HNC upper aerodigestive tract GDSC10001
TE-8 oesophagus GDSC10001
BE-13 haematopoietic and lymphoid tissue GDSC10001
KALS-1 central nervous system GDSC10001
Download CSV
Download Data as CSV

Top molecular features associated with response to AZ628


Feature TypeStandardized
Nominal ANOVA
mRNA TNFRSF1A GDSC1000 AAC 0.31 3e-09
mRNA ACTN1 GDSC1000 AAC 0.36 3e-09
mRNA GCH1 GDSC1000 AAC -0.3 4e-09
mRNA PELI1 GDSC1000 AAC -0.29 4e-09
mRNA DAAM1 GDSC1000 AAC -0.3 6e-09
mRNA MFSD12 GDSC1000 AAC 0.33 6e-09
mRNA ETV4 GDSC1000 AAC 0.31 7e-09
mRNA CD68 GDSC1000 AAC 0.31 9e-09
mRNA PYGL GDSC1000 AAC 0.29 1e-08
mRNA MMP14 GDSC1000 AAC 0.36 1e-08
Download CSV