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necrostatin-1

Synonyms

SourcesNames Used
CTRPv2necrostatin-1
PharmacoGx necrostatin-1

External IDs

DatabaseIdentifier
Smiles: CN1C(=O)C(NC1=S)CC2=CNC3=CC=CC=C32
Inchikey: TXUWMXQFNYDOEZ-UHFFFAOYSA-N
Pubchem: 2828334

Annotated Targets

RIPK1

Cell lines tested with necrostatin-1

797 cell lines have been tested with this compound, using data from 1 dataset(s).
A549 lung CTRPv23
DU-145 prostate CTRPv22
AsPC-1 pancreas CTRPv22
NCI-H1869 lung CTRPv22
CCF-STTG1 central nervous system CTRPv22
OAW-28 ovary CTRPv22
HeLa cervix CTRPv22
LOXIMVI haematopoietic and lymphoid tissue CTRPv22
NCI-H520 lung CTRPv22
MKN74 stomach CTRPv22
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Top molecular features associated with response to necrostatin-1


Feature TypeStandardized
Nominal ANOVA
mRNA DYRK1B CTRPv2 AAC 0.14 0.0002
mRNA POP4 CTRPv2 AAC 0.14 0.0002
mRNA RSC1A1 CTRPv2 AAC 0.14 0.0002
mRNA PMM1 CTRPv2 AAC -0.14 0.0002
mRNA C6 CTRPv2 AAC 0.14 0.0002
mRNA TMEM109 CTRPv2 AAC 0.14 0.0002
mRNA NDNF CTRPv2 AAC 0.13 0.0003
mRNA ALG8 CTRPv2 AAC 0.13 0.0003
mRNA CNDP2 CTRPv2 AAC 0.14 0.0003
mRNA BLNK CTRPv2 AAC 0.14 0.0003
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