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necrostatin-1

Synonyms

SourcesNames Used
CTRPv2necrostatin-1
PharmacoGx necrostatin-1

External IDs

DatabaseIdentifier
Smiles: CN1C(=O)C(NC1=S)CC2=CNC3=CC=CC=C32
Inchikey: TXUWMXQFNYDOEZ-UHFFFAOYSA-N
Pubchem: 2828334

Annotated Targets

RIPK1

Cell lines tested with necrostatin-1

797 cell lines have been tested with this compound, using data from 1 dataset(s).
A549 lung CTRPv23
DU-145 prostate CTRPv22
AsPC-1 pancreas CTRPv22
NCI-H1869 lung CTRPv22
CCF-STTG1 central nervous system CTRPv22
OAW-28 ovary CTRPv22
HeLa cervix CTRPv22
LOXIMVI haematopoietic and lymphoid tissue CTRPv22
NCI-H520 lung CTRPv22
MKN74 stomach CTRPv22
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Top molecular features associated with response to necrostatin-1


Feature TypeStandardized
Nominal ANOVA
mRNA GPR142 CTRPv2 AAC 0.15 5e-05
mRNA NARS2 CTRPv2 AAC 0.15 6e-05
mRNA URB2 CTRPv2 AAC 0.16 7e-05
mRNA BTRC CTRPv2 AAC 0.14 9e-05
mRNA PRDM15 CTRPv2 AAC 0.15 0.0001
mRNA NCAN CTRPv2 AAC 0.14 0.0001
mRNA ZNF124 CTRPv2 AAC 0.16 0.0001
mRNA OR5AK2 CTRPv2 AAC 0.14 0.0002
mRNA TIMM21 CTRPv2 AAC 0.14 0.0002
mRNA ZNF407 CTRPv2 AAC 0.15 0.0002
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