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necrostatin-1

Synonyms

SourcesNames Used
CTRPv2necrostatin-1
PharmacoGx necrostatin-1

External IDs

DatabaseIdentifier
Smiles: CN1C(=O)C(NC1=S)CC2=CNC3=CC=CC=C32
Inchikey: TXUWMXQFNYDOEZ-UHFFFAOYSA-N
Pubchem: 2828334

Annotated Targets

RIPK1

Cell lines tested with necrostatin-1

797 cell lines have been tested with this compound, using data from 1 dataset(s).
A549 lung CTRPv23
DU-145 prostate CTRPv22
AsPC-1 pancreas CTRPv22
NCI-H1869 lung CTRPv22
CCF-STTG1 central nervous system CTRPv22
OAW-28 ovary CTRPv22
HeLa cervix CTRPv22
LOXIMVI haematopoietic and lymphoid tissue CTRPv22
NCI-H520 lung CTRPv22
MKN74 stomach CTRPv22
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Top molecular features associated with response to necrostatin-1


Feature TypeStandardized
Nominal ANOVA
mRNA ARAF CTRPv2 AAC 1.9e-05 1
mRNA AP3D1 CTRPv2 AAC 1.8e-05 1
mRNA ZNF773 CTRPv2 AAC -1.8e-05 1
mRNA SERPINB3 CTRPv2 AAC 1.5e-05 1
mRNA OR6C2 CTRPv2 AAC -1.5e-05 1
mRNA HNRNPF CTRPv2 AAC -1.6e-05 1
mRNA STON1 CTRPv2 AAC 1.3e-05 1
mRNA GOLGA2 CTRPv2 AAC -1.2e-05 1
mRNA TRIM68 CTRPv2 AAC -1e-05 1
mRNA CPEB1 CTRPv2 AAC -3.8e-06 1
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