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SourcesNames Used
PharmacoGx necrostatin-1

External IDs

Smiles: CN1C(=O)C(NC1=S)CC2=CNC3=CC=CC=C32
Pubchem: 2828334

Annotated Targets


Cell lines tested with necrostatin-1

797 cell lines have been tested with this compound, using data from 1 dataset(s).
A549 lung CTRPv23
DU-145 prostate CTRPv22
AsPC-1 pancreas CTRPv22
NCI-H1869 lung CTRPv22
CCF-STTG1 central nervous system CTRPv22
OAW-28 ovary CTRPv22
HeLa cervix CTRPv22
LOXIMVI haematopoietic and lymphoid tissue CTRPv22
NCI-H520 lung CTRPv22
MKN74 stomach CTRPv22
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Top molecular features associated with response to necrostatin-1

Feature TypeStandardized
Nominal ANOVA
mRNA STAC2 CTRPv2 AAC 0.18 2e-06
mRNA PHACTR1 CTRPv2 AAC 0.2 4e-06
mRNA FAM129C CTRPv2 AAC 0.17 5e-06
mRNA ABC13-47656900H15.1 CTRPv2 AAC 0.16 7e-06
mRNA GHRH CTRPv2 AAC 0.16 1e-05
mRNA RGR CTRPv2 AAC 0.15 3e-05
mRNA DDI2 CTRPv2 AAC 0.16 3e-05
mRNA PHF24 CTRPv2 AAC 0.15 3e-05
mRNA SLC26A5 CTRPv2 AAC 0.15 4e-05
mRNA AHCTF1 CTRPv2 AAC 0.15 5e-05
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