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necrostatin-1

Synonyms

SourcesNames Used
CTRPv2necrostatin-1
PharmacoGx necrostatin-1

External IDs

DatabaseIdentifier
Smiles: CN1C(=O)C(NC1=S)CC2=CNC3=CC=CC=C32
Inchikey: TXUWMXQFNYDOEZ-UHFFFAOYSA-N
Pubchem: 2828334

Annotated Targets

RIPK1

Cell lines tested with necrostatin-1

797 cell lines have been tested with this compound, using data from 1 dataset(s).
A549 lung CTRPv23
DU-145 prostate CTRPv22
AsPC-1 pancreas CTRPv22
NCI-H1869 lung CTRPv22
CCF-STTG1 central nervous system CTRPv22
OAW-28 ovary CTRPv22
HeLa cervix CTRPv22
LOXIMVI haematopoietic and lymphoid tissue CTRPv22
NCI-H520 lung CTRPv22
MKN74 stomach CTRPv22
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Top molecular features associated with response to necrostatin-1


Feature TypeStandardized
Nominal ANOVA
mRNA PMM1 CTRPv2 AAC -0.14 0.0002
mRNA NUDT18 CTRPv2 AAC -0.14 0.0003
mRNA MYO1B CTRPv2 AAC -0.14 0.002
mRNA ADK CTRPv2 AAC -0.13 0.0007
mRNA TTC23 CTRPv2 AAC -0.13 0.001
mRNA TRIM7 CTRPv2 AAC -0.13 0.001
mRNA DBNDD2 CTRPv2 AAC -0.13 0.002
mRNA DLC1 CTRPv2 AAC -0.13 0.001
mRNA TRIOBP CTRPv2 AAC -0.12 0.002
mRNA KNSTRN CTRPv2 AAC -0.12 0.001
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